Description
PT-141 (Bremelanotide) – Melanocortin Receptor Modulation Peptide
Composition: PT-141 (10 mg lyophilized peptide powder)
Category: Peptide
Form: 10 mg vial with freeze-dried powder
Administration: Subcutaneous research application after reconstitution with sterile or bacteriostatic water (depending on study design)
What is PT-141?
PT-141, also known as Bremelanotide, is a synthetic peptide derived from melanocortin analogues and is specifically designed to interact with melanocortin receptors (MC3R, MC4R) in the central nervous system.
Unlike peptides that act through hormonal or vascular pathways, PT-141 has been studied for its direct central nervous system activity, particularly in relation to behavioral and neuroendocrine signaling mechanisms.
In research settings, PT-141 (10 mg) is widely investigated for its effects on central arousal pathways, motivational signaling, and melanocortin-mediated neurotransmission, making it a well-established compound in neurobiology and behavioral science research.
➡️ Ideal for neuroendocrine research, melanocortin receptor studies, and CNS signaling investigations.
Key Research Findings
Central Melanocortin Activation: Demonstrates high affinity for MC3R and MC4R receptors.
Neurotransmitter Pathway Modulation: Influences central signaling involved in motivation and arousal-related behaviors.
Non-Hormonal Mechanism: Does not rely on direct hormonal modulation or peripheral vasodilation pathways.
Rapid CNS Activity Profile: Shows fast onset of action in experimental research models.
High Research Interest: Extensively studied in neurobiology, behavioral science, and receptor pharmacology.
Mechanism of Action
PT-141 acts by activating melanocortin receptors in the central nervous system, leading to:
Melanocortin Receptor Stimulation → Activation of MC3R and MC4R pathways
Central Neurotransmitter Modulation → Altered signaling in motivation and arousal circuits
CNS-Focused Activity → Primary effects mediated centrally rather than peripherally
Receptor-Specific Action Profile → Targeted interaction without direct hormonal pathway involvement
Dosage & Application
Reconstitute with sterile or bacteriostatic water before use.
Typical research concentrations depend on experimental design and protocol requirements.
A 10 mg vial is suitable for multiple research applications, dose-response studies, or extended experimental protocols.
Store the reconstituted solution refrigerated and use within 2–3 weeks.
Storage Instructions
Store at 2–8 °C (36–46 °F)
Protect from light and moisture
Do not freeze
Use reconstituted solution within 2–3 weeks
Why Choose PT-141 (10 mg)?
PT-141 is valued for its unique central mechanism of action targeting melanocortin receptors rather than peripheral or hormonal systems.
This makes it especially relevant for advanced research into CNS signaling, receptor pharmacology, and neurobehavioral pathways.
It is widely respected in scientific research for its receptor specificity, central activity profile, and strong relevance to melanocortin-based investigations.
Order PT-141 (10 mg) and explore its potential in advanced melanocortin receptor research, CNS signaling studies, and neuroendocrine investigations.





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