{"id":39654,"date":"2026-01-28T22:33:19","date_gmt":"2026-01-28T21:33:19","guid":{"rendered":"https:\/\/europa-peptide.com\/?post_type=product&#038;p=39654"},"modified":"2026-06-14T00:39:52","modified_gmt":"2026-06-13T22:39:52","slug":"pe-22-28-10mg","status":"publish","type":"product","link":"https:\/\/europa-peptide.com\/es\/shop\/pe-22-28-10mg\/","title":{"rendered":"PE 22-28 10 mg"},"content":{"rendered":"<p data-start=\"142\" data-end=\"209\"><strong data-start=\"142\" data-end=\"209\">PE-22-28 - Compuesto de investigaci\u00f3n del neurop\u00e9ptido derivado de la proenkefalina<\/strong><\/p>\n<p data-start=\"211\" data-end=\"496\"><strong data-start=\"211\" data-end=\"227\">Composici\u00f3n:<\/strong> PE-22-28 (10 mg de p\u00e9ptido liofilizado en polvo)<br data-start=\"271\" data-end=\"274\" \/><strong data-start=\"274\" data-end=\"287\">Categor\u00eda:<\/strong> P\u00e9ptido<br data-start=\"295\" data-end=\"298\" \/><strong data-start=\"298\" data-end=\"307\">Forma:<\/strong> 10 mg vial con polvo liofilizado<br data-start=\"343\" data-end=\"346\" \/><strong data-start=\"346\" data-end=\"365\">Administraci\u00f3n:<\/strong> Aplicaci\u00f3n subcut\u00e1nea o central de investigaci\u00f3n tras reconstituci\u00f3n con agua est\u00e9ril o bacteriost\u00e1tica (dependiendo del dise\u00f1o del estudio).<\/p>\n<hr data-start=\"498\" data-end=\"501\" \/>\n<h3 data-start=\"503\" data-end=\"524\">\u00bfQu\u00e9 es el PE-22-28?<\/h3>\n<p data-start=\"526\" data-end=\"700\">PE-22-28 es un <strong data-start=\"540\" data-end=\"575\">fragmento sint\u00e9tico de neurop\u00e9ptido<\/strong> derivado de <strong data-start=\"589\" data-end=\"608\">Proenkefalina A<\/strong>, una prote\u00edna precursora end\u00f3gena implicada en las v\u00edas de se\u00f1alizaci\u00f3n opioide y neurorreguladora.<\/p>\n<p data-start=\"702\" data-end=\"1050\">Este p\u00e9ptido se ha estudiado por su papel en <strong data-start=\"748\" data-end=\"785\">modulaci\u00f3n del sistema nervioso central<\/strong>, especialmente en relaci\u00f3n con <strong data-start=\"815\" data-end=\"891\">equilibrio dopamin\u00e9rgico, regulaci\u00f3n de la prolactina y se\u00f1alizaci\u00f3n neuroendocrina<\/strong>.<br data-start=\"892\" data-end=\"895\" \/>A diferencia de los p\u00e9ptidos opioides cl\u00e1sicos, el PE-22-28 demuestra <strong data-start=\"951\" data-end=\"989\">no analg\u00e9sico, actividad reguladora<\/strong>, lo que lo convierte en un compuesto distinto dentro de la investigaci\u00f3n de los neurop\u00e9ptidos.<\/p>\n<p data-start=\"1052\" data-end=\"1225\">En entornos de investigaci\u00f3n, se investiga la influencia del PE-22-28 (10 mg) sobre <strong data-start=\"1128\" data-end=\"1224\">regulaci\u00f3n de neurotransmisores, se\u00f1alizaci\u00f3n motivacional e interacciones hipot\u00e1lamo-hipofisarias<\/strong>.<\/p>\n<p data-start=\"1227\" data-end=\"1328\">\u27a1\ufe0f Ideal para la investigaci\u00f3n de neurop\u00e9ptidos, estudios de se\u00f1alizaci\u00f3n del SNC e investigaciones de v\u00edas neuroendocrinas.<\/p>\n<hr data-start=\"1330\" data-end=\"1333\" \/>\n<h3 data-start=\"1335\" data-end=\"1360\">Principales resultados de la investigaci\u00f3n<\/h3>\n<p data-start=\"1362\" data-end=\"1460\">Actividad neurorreguladora: Estudiado por su papel modulador dentro de los sistemas neurotransmisores centrales.<\/p>\n<p data-start=\"1462\" data-end=\"1576\">Interacci\u00f3n dopamin\u00e9rgica: Asociada a la regulaci\u00f3n de las v\u00edas de se\u00f1alizaci\u00f3n vinculadas a la dopamina en modelos experimentales.<\/p>\n<p data-start=\"1578\" data-end=\"1687\">Investigaci\u00f3n sobre la modulaci\u00f3n de la prolactina: Se investiga su influencia en los mecanismos neuroendocrinos relacionados con la prolactina.<\/p>\n<p data-start=\"1689\" data-end=\"1771\">Perfil funcional no opioide: No presenta agonismo cl\u00e1sico de los receptores opioides.<\/p>\n<p data-start=\"1773\" data-end=\"1865\">Inter\u00e9s espec\u00edfico del SNC: Principalmente relevante para modelos de investigaci\u00f3n centrales m\u00e1s que perif\u00e9ricos.<\/p>\n<hr data-start=\"1867\" data-end=\"1870\" \/>\n<h3 data-start=\"1872\" data-end=\"1895\">Mecanismo de acci\u00f3n<\/h3>\n<p data-start=\"1897\" data-end=\"1993\">Se cree que el PE-22-28 ejerce sus efectos a trav\u00e9s de mecanismos neurorreguladores centrales, entre los que se incluyen:<\/p>\n<p data-start=\"1995\" data-end=\"2092\">Modulaci\u00f3n de neurotransmisores \u2192 Interacci\u00f3n con circuitos de se\u00f1alizaci\u00f3n dopamin\u00e9rgica y neuroendocrina<\/p>\n<p data-start=\"2094\" data-end=\"2177\">Influencia de la v\u00eda hipotal\u00e1mica \u2192 Modulaci\u00f3n de las cascadas de se\u00f1alizaci\u00f3n relacionadas con la hip\u00f3fisis<\/p>\n<p data-start=\"2179\" data-end=\"2256\">Regulaci\u00f3n mediada por receptores \u2192 Interacci\u00f3n indirecta con los sistemas receptores del SNC<\/p>\n<p data-start=\"2258\" data-end=\"2334\">Perfil de actividad central \u2192 Efectos focalizados en el sistema nervioso central<\/p>\n<hr data-start=\"2336\" data-end=\"2339\" \/>\n<h3 data-start=\"2341\" data-end=\"2365\">Posolog\u00eda y aplicaci\u00f3n<\/h3>\n<p data-start=\"2367\" data-end=\"2428\">Reconstituir con agua est\u00e9ril o bacteriost\u00e1tica antes de usar.<\/p>\n<p data-start=\"2430\" data-end=\"2639\">Las concentraciones de investigaci\u00f3n var\u00edan en funci\u00f3n del dise\u00f1o experimental y los requisitos del protocolo.<br data-start=\"2518\" data-end=\"2521\" \/>Un vial de 10 mg es adecuado para m\u00faltiples estudios de neurop\u00e9ptidos, experimentos de dosis-respuesta o protocolos de investigaci\u00f3n ampliados.<\/p>\n<p data-start=\"2641\" data-end=\"2712\">Conservar la soluci\u00f3n reconstituida refrigerada y utilizar en 2-3 semanas.<\/p>\n<hr data-start=\"2714\" data-end=\"2717\" \/>\n<h3 data-start=\"2719\" data-end=\"2743\">Instrucciones de almacenamiento<\/h3>\n<p data-start=\"2745\" data-end=\"2867\">Conservar a 2-8 \u00b0C (36-46 \u00b0F)<br data-start=\"2771\" data-end=\"2774\" \/>Proteger de la luz y la humedad<br data-start=\"2805\" data-end=\"2808\" \/>No congelar<br data-start=\"2821\" data-end=\"2824\" \/>Utilizar la soluci\u00f3n reconstituida en 2-3 semanas<\/p>\n<hr data-start=\"2869\" data-end=\"2872\" \/>\n<h3 data-start=\"2874\" data-end=\"2906\">\u00bfPor qu\u00e9 elegir PE-22-28 (10 mg)?<\/h3>\n<p data-start=\"2908\" data-end=\"3148\">El PE-22-28 se valora en los entornos de investigaci\u00f3n por su <strong data-start=\"2960\" data-end=\"3022\">posici\u00f3n \u00fanica dentro de los neurop\u00e9ptidos derivados de la proenkefalina<\/strong>, que ofrece informaci\u00f3n sobre <strong data-start=\"3046\" data-end=\"3117\">v\u00edas neuroendocrinas reguladas por la dopamina y asociadas a la prolactina<\/strong> sin efectos opi\u00e1ceos directos.<\/p>\n<p data-start=\"3150\" data-end=\"3335\">Su especificidad y su perfil de actividad central lo hacen especialmente pertinente para <strong data-start=\"3229\" data-end=\"3334\">investigaci\u00f3n avanzada sobre el SNC, estudios sobre la se\u00f1alizaci\u00f3n de neurop\u00e9ptidos e investigaciones sobre el eje hipotal\u00e1mico-hipofisario<\/strong>.<\/p>\n<p data-start=\"3337\" data-end=\"3483\"><strong data-start=\"3337\" data-end=\"3363\">Pedido PE-22-28 (10 mg)<\/strong> y explorar su potencial en la investigaci\u00f3n avanzada de neurop\u00e9ptidos, el an\u00e1lisis de la se\u00f1alizaci\u00f3n del SNC y las investigaciones neuroendocrinas.<\/p>","protected":false},"excerpt":{"rendered":"<p>PE-22-28 \u2013 Compuesto de investigaci\u00f3n derivado de la proencefalina Composici\u00f3n: PE-22-28 (10 mg de p\u00e9ptido liofilizado en polvo) Categor\u00eda: P\u00e9ptido Forma: Vial de 10 mg con polvo liofilizado Administraci\u00f3n: Aplicaci\u00f3n subcut\u00e1nea o central para investigaci\u00f3n tras reconstituci\u00f3n con agua est\u00e9ril o bacteriost\u00e1tica (dependiendo del dise\u00f1o del estudio) \u00bfQu\u00e9 es el PE-22-28? El PE-22-28 es un fragmento de neurop\u00e9ptido sint\u00e9tico derivado de la proencefalina A, una prote\u00edna precursora end\u00f3gena implicada en las v\u00edas de se\u00f1alizaci\u00f3n opioides y neurorreguladoras. Este p\u00e9ptido ha sido estudiado por su papel en la modulaci\u00f3n del sistema nervioso central, particularmente en relaci\u00f3n con el equilibrio dopamin\u00e9rgico, la regulaci\u00f3n de la prolactina y la se\u00f1alizaci\u00f3n neuroendocrina. A diferencia de los p\u00e9ptidos opioides cl\u00e1sicos, el PE-22-28 muestra una actividad reguladora no analg\u00e9sica, lo que lo convierte en un compuesto distintivo dentro de la investigaci\u00f3n sobre neurop\u00e9ptidos. En entornos de investigaci\u00f3n, se estudia el PE-22-28 (10 mg) por su influencia en la regulaci\u00f3n de los neurotransmisores, la se\u00f1alizaci\u00f3n motivacional y las interacciones hipot\u00e1lamo-hipofisarias. \u27a1\ufe0f Ideal para la investigaci\u00f3n de neurop\u00e9ptidos, estudios de se\u00f1alizaci\u00f3n del SNC e investigaciones de las v\u00edas neuroendocrinas. Hallazgos clave de la investigaci\u00f3n Actividad neurorreguladora: Se ha estudiado por su papel modulador dentro de los sistemas neurotransmisores centrales. Interacci\u00f3n dopamin\u00e9rgica: Se asocia con la regulaci\u00f3n de las v\u00edas de se\u00f1alizaci\u00f3n relacionadas con la dopamina en modelos experimentales. Investigaci\u00f3n sobre la modulaci\u00f3n de la prolactina: Se investiga su influencia en los mecanismos neuroendocrinos relacionados con la prolactina. Perfil funcional no opioide: No muestra agonismo cl\u00e1sico de los receptores opioides. Inter\u00e9s espec\u00edfico para el SNC: Relevante principalmente para modelos de investigaci\u00f3n centrales, m\u00e1s que perif\u00e9ricos. Mecanismo de acci\u00f3n: Se cree que el PE-22-28 ejerce sus efectos a trav\u00e9s de mecanismos neurorreguladores centrales, entre los que se incluyen: Modulaci\u00f3n de neurotransmisores \u2192 Interacci\u00f3n con circuitos de se\u00f1alizaci\u00f3n dopamin\u00e9rgicos y neuroendocrinos. Influencia en la v\u00eda hipotal\u00e1mica \u2192 Modulaci\u00f3n de lasRegulaci\u00f3n mediada por receptores \u2192 Interacci\u00f3n indirecta con los sistemas de receptores del SNC Perfil de actividad central \u2192 Efectos centrados en el sistema nervioso central Dosificaci\u00f3n y aplicaci\u00f3n Reconstituir con agua est\u00e9ril o bacteriost\u00e1tica antes de su uso. Las concentraciones de investigaci\u00f3n var\u00edan en funci\u00f3n del dise\u00f1o experimental y los requisitos del protocolo. Un vial de 10 mg es adecuado para m\u00faltiples estudios de neurop\u00e9ptidos, experimentos de respuesta a la dosis o protocolos de investigaci\u00f3n prolongados. Conservar la soluci\u00f3n reconstituida en el frigor\u00edfico y utilizarla en un plazo de 2 a 3 semanas. Instrucciones de almacenamiento: Conservar a 2-8 \u00b0C (36-46 \u00b0F). Proteger de la luz y la humedad. No congelar. Utilizar la soluci\u00f3n reconstituida en un plazo de 2 a 3 semanas. \u00bfPor qu\u00e9 elegir PE-22-28 (10 mg)? El PE-22-28 es muy valorado en entornos de investigaci\u00f3n por su posici\u00f3n \u00fanica entre los neurop\u00e9ptidos derivados de la proencefalina, ya que ofrece informaci\u00f3n sobre las v\u00edas neuroendocrinas reguladas por la dopamina y asociadas a la prolactina sin efectos opioides directos. Su especificidad y su perfil de actividad central lo hacen especialmente relevante para la investigaci\u00f3n avanzada del SNC, los estudios de se\u00f1alizaci\u00f3n de neurop\u00e9ptidos y las investigaciones del eje hipot\u00e1lamo-hipofisario. Pida PE-22-28 (10 mg) y explore su potencial en la investigaci\u00f3n avanzada de neurop\u00e9ptidos, el an\u00e1lisis de la se\u00f1alizaci\u00f3n del SNC y las investigaciones neuroendocrinas.<\/p>","protected":false},"featured_media":126807,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_brand":[],"product_cat":[17,26,27],"product_tag":[],"class_list":["post-39654","product","type-product","status-publish","has-post-thumbnail","product_cat-all-products","product_cat-neuroandvascularprotection","product_cat-peptidesandresearchdrugs","entry","has-media","first","instock","shipping-taxable","purchasable","product-type-simple"],"acf":[],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 4.9.8 - aioseo.com -->\n\t<meta name=\"description\" content=\"PE-22-28 \u2013 Proenkephalin-Derived Neuropeptide Research Compound Composition: PE-22-28 (10 mg lyophilized peptide powder)Category: PeptideForm: 10 mg vial with freeze-dried powderAdministration: Subcutaneous or central research application after reconstitution with sterile or bacteriostatic water (depending on study design) What is PE-22-28? PE-22-28 is a synthetic neuropeptide fragment derived from Proenkephalin A, an endogenous precursor protein involved in\" \/>\n\t<meta name=\"robots\" content=\"max-image-preview:large\" \/>\n\t<link rel=\"canonical\" href=\"https:\/\/europa-peptide.com\/es\/shop\/pe-22-28-10mg\/\" \/>\n\t<meta name=\"generator\" content=\"All in One SEO (AIOSEO) 4.9.8\" \/>\n\t\t<meta property=\"og:locale\" content=\"es_ES\" \/>\n\t\t<meta property=\"og:site_name\" content=\"Europa-Peptide - Europa-Peptide\" \/>\n\t\t<meta property=\"og:type\" content=\"article\" \/>\n\t\t<meta property=\"og:title\" content=\"PE 22-28 10mg - Europa-Peptide\" \/>\n\t\t<meta property=\"og:description\" content=\"PE-22-28 \u2013 Proenkephalin-Derived Neuropeptide Research Compound Composition: PE-22-28 (10 mg lyophilized peptide powder)Category: PeptideForm: 10 mg vial with freeze-dried powderAdministration: Subcutaneous or central research application after reconstitution with sterile or bacteriostatic water (depending on study design) What is PE-22-28? 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