{"id":39654,"date":"2026-01-28T22:33:19","date_gmt":"2026-01-28T21:33:19","guid":{"rendered":"https:\/\/europa-peptide.com\/?post_type=product&p=39654"},"modified":"2026-05-16T14:16:30","modified_gmt":"2026-05-16T12:16:30","slug":"pe-22-28-10mg","status":"publish","type":"product","link":"https:\/\/europa-peptide.com\/fr\/shop\/pe-22-28-10mg\/","title":{"rendered":"PE 22-28 10mg"},"content":{"rendered":"

PE-22-28 - Compos\u00e9 de recherche sur les neuropeptides d\u00e9riv\u00e9s de la proenk\u00e9phaline<\/strong><\/p>\n

Composition :<\/strong> PE-22-28 (10 mg de poudre de peptide lyophilis\u00e9e)
Cat\u00e9gorie :<\/strong> Peptide
Forme :<\/strong> Flacon de 10 mg avec poudre lyophilis\u00e9e
Administration :<\/strong> Application sous-cutan\u00e9e ou recherche centrale apr\u00e8s reconstitution avec de l'eau st\u00e9rile ou bact\u00e9riostatique (en fonction de la conception de l'\u00e9tude)<\/p>\n

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Qu'est-ce que le PE-22-28 ?<\/h3>\n

PE-22-28 est un fragment synth\u00e9tique de neuropeptide<\/strong> d\u00e9riv\u00e9 de Proenk\u00e9phaline A<\/strong>, une prot\u00e9ine pr\u00e9curseur endog\u00e8ne impliqu\u00e9e dans les voies de signalisation opio\u00efdes et neuror\u00e9gulatrices.<\/p>\n

Ce peptide a \u00e9t\u00e9 \u00e9tudi\u00e9 pour son r\u00f4le dans le modulation du syst\u00e8me nerveux central<\/strong>, en particulier en ce qui concerne \u00e9quilibre dopaminergique, r\u00e9gulation de la prolactine et signalisation neuroendocrine<\/strong>.
Contrairement aux peptides opio\u00efdes classiques, le PE-22-28 pr\u00e9sente les caract\u00e9ristiques suivantes non analg\u00e9sique, activit\u00e9 r\u00e9gulatrice<\/strong>, ce qui en fait un compos\u00e9 \u00e0 part dans la recherche sur les neuropeptides.<\/p>\n

Dans le cadre de la recherche, le PE-22-28 (10 mg) est \u00e9tudi\u00e9 pour son influence sur la r\u00e9gulation des neurotransmetteurs, la signalisation de la motivation et les interactions entre l'hypothalamus et l'hypophyse<\/strong>.<\/p>\n

\u27a1\ufe0f Id\u00e9al pour la recherche sur les neuropeptides, les \u00e9tudes sur la signalisation du SNC et les \u00e9tudes sur les voies neuroendocrines.<\/p>\n

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Principaux r\u00e9sultats de la recherche<\/h3>\n

Activit\u00e9 neuro-r\u00e9gulatrice : \u00c9tudi\u00e9 pour son r\u00f4le modulateur dans les syst\u00e8mes de neurotransmetteurs centraux.<\/p>\n

Interaction dopaminergique : Associ\u00e9 \u00e0 la r\u00e9gulation des voies de signalisation li\u00e9es \u00e0 la dopamine dans des mod\u00e8les exp\u00e9rimentaux.<\/p>\n

Recherche sur la modulation de la prolactine : \u00c9tude de son influence sur les m\u00e9canismes neuroendocriniens li\u00e9s \u00e0 la prolactine.<\/p>\n

Profil fonctionnel non opio\u00efde : Ne pr\u00e9sente pas d'agonisme classique des r\u00e9cepteurs opio\u00efdes.<\/p>\n

Int\u00e9r\u00eat pour le SNC : Principalement pertinent pour les mod\u00e8les de recherche centraux plut\u00f4t que p\u00e9riph\u00e9riques.<\/p>\n

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M\u00e9canisme d'action<\/h3>\n

On pense que le PE-22-28 exerce ses effets par le biais de m\u00e9canismes neuror\u00e9gulateurs centraux, notamment :<\/p>\n

Modulation des neurotransmetteurs \u2192 Interaction avec les circuits de signalisation dopaminergiques et neuroendocriniens<\/p>\n

Influence de la voie hypothalamique \u2192 Modulation des cascades de signalisation li\u00e9es \u00e0 l'hypophyse<\/p>\n

R\u00e9gulation m\u00e9di\u00e9e par les r\u00e9cepteurs \u2192 Interaction indirecte avec les syst\u00e8mes de r\u00e9cepteurs du SNC<\/p>\n

Profil d'activit\u00e9 centrale \u2192 Effets cibl\u00e9s sur le syst\u00e8me nerveux central<\/p>\n

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Dosage et application<\/h3>\n

Reconstituer avec de l'eau st\u00e9rile ou bact\u00e9riostatique avant utilisation.<\/p>\n

Les concentrations de recherche varient en fonction de la conception exp\u00e9rimentale et des exigences du protocole.
Le flacon de 10 mg convient aux \u00e9tudes sur les neuropeptides multiples, aux exp\u00e9riences dose-r\u00e9ponse ou aux protocoles de recherche \u00e9tendus.<\/p>\n

Conserver la solution reconstitu\u00e9e au r\u00e9frig\u00e9rateur et l'utiliser dans les 2 \u00e0 3 semaines.<\/p>\n

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Instructions de stockage<\/h3>\n

A conserver entre 2 et 8 \u00b0C (36-46 \u00b0F)
Prot\u00e9ger de la lumi\u00e8re et de l'humidit\u00e9
Ne pas congeler
Utiliser la solution reconstitu\u00e9e dans les 2 \u00e0 3 semaines<\/p>\n

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Pourquoi choisir le PE-22-28 (10 mg) ?<\/h3>\n

Le PE-22-28 est appr\u00e9ci\u00e9 dans les environnements de recherche pour son position unique au sein des neuropeptides d\u00e9riv\u00e9s de la proenk\u00e9phaline<\/strong>, La Commission europ\u00e9enne a publi\u00e9 un rapport sur les les voies neuroendocriniennes r\u00e9gul\u00e9es par la dopamine et associ\u00e9es \u00e0 la prolactine<\/strong> sans effets opio\u00efdes directs.<\/p>\n

Sa sp\u00e9cificit\u00e9 et son profil d'activit\u00e9 centrale le rendent particuli\u00e8rement pertinent pour recherche avanc\u00e9e sur le SNC, \u00e9tudes sur la signalisation des neuropeptides et recherches sur l'axe hypothalamo-hypophysaire<\/strong>.<\/p>\n

Commander PE-22-28 (10 mg)<\/strong> et explorer son potentiel dans la recherche avanc\u00e9e sur les neuropeptides, l'analyse des signaux du SNC et les investigations neuroendocriniennes.<\/p>","protected":false},"excerpt":{"rendered":"

PE-22-28 \u2013 Proenkephalin-Derived Neuropeptide Research Compound Composition: PE-22-28 (10 mg lyophilized peptide powder)Category: PeptideForm: 10 mg vial with freeze-dried powderAdministration: Subcutaneous or central research application after reconstitution with sterile or bacteriostatic water (depending on study design) What is PE-22-28? PE-22-28 is a synthetic neuropeptide fragment derived from Proenkephalin A, an endogenous precursor protein involved in opioid and neuroregulatory signaling pathways. This peptide has been studied for its role in central nervous system modulation, particularly in relation to dopaminergic balance, prolactin regulation, and neuroendocrine signaling.Unlike classical opioid peptides, PE-22-28 demonstrates non-analgesic, regulatory activity, making it a distinct compound within neuropeptide research. In research settings, PE-22-28 (10 mg) is investigated for its influence on neurotransmitter regulation, motivational signaling, and hypothalamic-pituitary interactions. \u27a1\ufe0f Ideal for neuropeptide research, CNS signaling studies, and neuroendocrine pathway investigations. Key Research Findings Neuroregulatory Activity: Studied for its modulatory role within central neurotransmitter systems. Dopaminergic Interaction: Associated with regulation of dopamine-linked signaling pathways in experimental models. Prolactin Modulation Research: Investigated for its influence on prolactin-related neuroendocrine mechanisms. Non-Opioid Functional Profile: Does not exhibit classical opioid receptor agonism. CNS-Specific Interest: Primarily relevant to central rather than peripheral research models. Mechanism of Action PE-22-28 is believed to exert its effects through central neuroregulatory mechanisms, including: Neurotransmitter Modulation \u2192 Interaction with dopaminergic and neuroendocrine signaling circuits Hypothalamic Pathway Influence \u2192 Modulation of pituitary-related signaling cascades Receptor-Mediated Regulation \u2192 Indirect interaction with CNS receptor systems Central Activity Profile \u2192 Focused effects within the central nervous system Dosage & Application Reconstitute with sterile or bacteriostatic water before use. Research concentrations vary depending on experimental design and protocol requirements.A 10 mg vial is suitable for multiple neuropeptide studies, dose-response experiments, or extended research protocols. Store the reconstituted solution refrigerated and use within 2\u20133 weeks. Storage Instructions Store at 2\u20138 \u00b0C (36\u201346 \u00b0F)Protect from light and moistureDo not freezeUse reconstituted solution within 2\u20133 weeks Why Choose PE-22-28 (10 mg)? PE-22-28 is valued in research environments for its unique position within proenkephalin-derived neuropeptides, offering insight into dopamine-regulated and prolactin-associated neuroendocrine pathways without direct opioid effects. Its specificity and central activity profile make it particularly relevant for advanced CNS research, neuropeptide signaling studies, and hypothalamic-pituitary axis investigations. Order PE-22-28 (10 mg) and explore its potential in advanced neuropeptide research, CNS signaling analysis, and neuroendocrine investigations.<\/p>","protected":false},"featured_media":39640,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_brand":[],"product_cat":[17,26,27],"product_tag":[],"class_list":{"0":"post-39654","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-all-products","7":"product_cat-neuroandvascularprotection","8":"product_cat-peptidesandresearchdrugs","9":"entry","10":"has-media","12":"first","13":"instock","14":"shipping-taxable","15":"purchasable","16":"product-type-simple"},"acf":[],"aioseo_notices":[],"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/europa-peptide.com\/fr\/wp-json\/wp\/v2\/product\/39654","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/europa-peptide.com\/fr\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/europa-peptide.com\/fr\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/europa-peptide.com\/fr\/wp-json\/wp\/v2\/comments?post=39654"}],"version-history":[{"count":1,"href":"https:\/\/europa-peptide.com\/fr\/wp-json\/wp\/v2\/product\/39654\/revisions"}],"predecessor-version":[{"id":39655,"href":"https:\/\/europa-peptide.com\/fr\/wp-json\/wp\/v2\/product\/39654\/revisions\/39655"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/europa-peptide.com\/fr\/wp-json\/wp\/v2\/media\/39640"}],"wp:attachment":[{"href":"https:\/\/europa-peptide.com\/fr\/wp-json\/wp\/v2\/media?parent=39654"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/europa-peptide.com\/fr\/wp-json\/wp\/v2\/product_brand?post=39654"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/europa-peptide.com\/fr\/wp-json\/wp\/v2\/product_cat?post=39654"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/europa-peptide.com\/fr\/wp-json\/wp\/v2\/product_tag?post=39654"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}