{"id":39654,"date":"2026-01-28T22:33:19","date_gmt":"2026-01-28T21:33:19","guid":{"rendered":"https:\/\/europa-peptide.com\/?post_type=product&#038;p=39654"},"modified":"2026-06-14T00:39:52","modified_gmt":"2026-06-13T22:39:52","slug":"pe-22-28-10mg","status":"publish","type":"product","link":"https:\/\/europa-peptide.com\/nl\/shop\/pe-22-28-10mg\/","title":{"rendered":"PE 22-28 10mg"},"content":{"rendered":"<p data-start=\"142\" data-end=\"209\"><strong data-start=\"142\" data-end=\"209\">PE-22-28 - onderzoekssamenstelling van proenkefaline afgeleid neuropeptide<\/strong><\/p>\n<p data-start=\"211\" data-end=\"496\"><strong data-start=\"211\" data-end=\"227\">Samenstelling:<\/strong> PE-22-28 (10 mg gevriesdroogd peptidepoeder)<br data-start=\"271\" data-end=\"274\" \/><strong data-start=\"274\" data-end=\"287\">Categorie:<\/strong> Peptide<br data-start=\"295\" data-end=\"298\" \/><strong data-start=\"298\" data-end=\"307\">Vorm:<\/strong> 10 mg injectieflacon met gevriesdroogd poeder<br data-start=\"343\" data-end=\"346\" \/><strong data-start=\"346\" data-end=\"365\">Administratie:<\/strong> Subcutane of centrale onderzoekstoepassing na reconstitutie met steriel of bacteriostatisch water (afhankelijk van de onderzoeksopzet)<\/p>\n<hr data-start=\"498\" data-end=\"501\" \/>\n<h3 data-start=\"503\" data-end=\"524\">Wat is PE-22-28?<\/h3>\n<p data-start=\"526\" data-end=\"700\">PE-22-28 is een <strong data-start=\"540\" data-end=\"575\">synthetisch neuropeptidefragment<\/strong> afgeleid van <strong data-start=\"589\" data-end=\"608\">Proenkefaline A<\/strong>, Een endogeen precursoreiwit dat betrokken is bij opio\u00efde en neuroregulerende signaalwegen.<\/p>\n<p data-start=\"702\" data-end=\"1050\">Deze peptide is bestudeerd voor zijn rol in <strong data-start=\"748\" data-end=\"785\">modulatie van het centrale zenuwstelsel<\/strong>, met name met betrekking tot <strong data-start=\"815\" data-end=\"891\">dopaminerge balans, prolactineregulatie en neuro-endocriene signalering<\/strong>.<br data-start=\"892\" data-end=\"895\" \/>In tegenstelling tot klassieke opio\u00efde peptiden laat PE-22-28 het volgende zien <strong data-start=\"951\" data-end=\"989\">niet-analgetische, regulerende activiteit<\/strong>, waardoor het een aparte verbinding is binnen het neuropeptide onderzoek.<\/p>\n<p data-start=\"1052\" data-end=\"1225\">In onderzoekssettings is PE-22-28 (10 mg) onderzocht op zijn invloed op <strong data-start=\"1128\" data-end=\"1224\">neurotransmitterregulatie, motivatiesignalering en hypothalamus-hypofyse-interacties<\/strong>.<\/p>\n<p data-start=\"1227\" data-end=\"1328\">\u27a1\ufe0f Ideaal voor neuropeptide-onderzoek, onderzoek naar CNS-signalering en onderzoek naar neuro-endocriene routes.<\/p>\n<hr data-start=\"1330\" data-end=\"1333\" \/>\n<h3 data-start=\"1335\" data-end=\"1360\">Belangrijkste onderzoeksresultaten<\/h3>\n<p data-start=\"1362\" data-end=\"1460\">Neuroregulerende activiteit: Bestudeerd voor zijn modulerende rol binnen centrale neurotransmittersystemen.<\/p>\n<p data-start=\"1462\" data-end=\"1576\">Dopaminerge interactie: Geassocieerd met regulatie van dopamine-gekoppelde signaalwegen in experimentele modellen.<\/p>\n<p data-start=\"1578\" data-end=\"1687\">Onderzoek naar prolactinemodulatie: Onderzocht op zijn invloed op prolactine-gerelateerde neuro-endocriene mechanismen.<\/p>\n<p data-start=\"1689\" data-end=\"1771\">Niet-opio\u00efde functioneel profiel: Vertoont geen klassiek opio\u00efde receptor agonisme.<\/p>\n<p data-start=\"1773\" data-end=\"1865\">CNS-specifiek belang: Voornamelijk relevant voor centrale in plaats van perifere onderzoeksmodellen.<\/p>\n<hr data-start=\"1867\" data-end=\"1870\" \/>\n<h3 data-start=\"1872\" data-end=\"1895\">Werkingsmechanisme<\/h3>\n<p data-start=\"1897\" data-end=\"1993\">Er wordt aangenomen dat PE-22-28 zijn effecten uitoefent via centrale neuroregulerende mechanismen, waaronder:<\/p>\n<p data-start=\"1995\" data-end=\"2092\">Modulatie van neurotransmitters \u2192 Interactie met dopaminerge en neuroendocriene signaalcircuits<\/p>\n<p data-start=\"2094\" data-end=\"2177\">Invloed hypothalamusroute \u2192 Modulatie van hypofyse-gerelateerde signaalcascades<\/p>\n<p data-start=\"2179\" data-end=\"2256\">Receptor-gemedieerde regulering \u2192 Indirecte interactie met CNS receptorsystemen<\/p>\n<p data-start=\"2258\" data-end=\"2334\">Centraal activiteitsprofiel \u2192 Gerichte effecten binnen het centrale zenuwstelsel<\/p>\n<hr data-start=\"2336\" data-end=\"2339\" \/>\n<h3 data-start=\"2341\" data-end=\"2365\">Dosering en toepassing<\/h3>\n<p data-start=\"2367\" data-end=\"2428\">Reconstitueer met steriel of bacteriostatisch water voor gebruik.<\/p>\n<p data-start=\"2430\" data-end=\"2639\">Onderzoeksconcentraties vari\u00ebren afhankelijk van het experimenteel ontwerp en de protocolvereisten.<br data-start=\"2518\" data-end=\"2521\" \/>Een 10 mg injectieflacon is geschikt voor meerdere neuropeptidestudies, dosis-respons experimenten of uitgebreide onderzoeksprotocollen.<\/p>\n<p data-start=\"2641\" data-end=\"2712\">Bewaar de gereconstitueerde oplossing gekoeld en gebruik binnen 2-3 weken.<\/p>\n<hr data-start=\"2714\" data-end=\"2717\" \/>\n<h3 data-start=\"2719\" data-end=\"2743\">Instructies voor opslag<\/h3>\n<p data-start=\"2745\" data-end=\"2867\">Bewaren bij 2-8 \u00b0C (36-46 \u00b0F)<br data-start=\"2771\" data-end=\"2774\" \/>Beschermen tegen licht en vocht<br data-start=\"2805\" data-end=\"2808\" \/>Niet invriezen<br data-start=\"2821\" data-end=\"2824\" \/>Gebruik gereconstitueerde oplossing binnen 2-3 weken<\/p>\n<hr data-start=\"2869\" data-end=\"2872\" \/>\n<h3 data-start=\"2874\" data-end=\"2906\">Waarom kiezen voor PE-22-28 (10 mg)?<\/h3>\n<p data-start=\"2908\" data-end=\"3148\">PE-22-28 wordt in onderzoeksomgevingen gewaardeerd om zijn <strong data-start=\"2960\" data-end=\"3022\">unieke positie binnen de van proenkefaline afgeleide neuropeptiden<\/strong>, biedt inzicht in <strong data-start=\"3046\" data-end=\"3117\">dopamine-gereguleerde en prolactine-geassocieerde neuro-endocriene routes<\/strong> zonder directe opio\u00efde effecten.<\/p>\n<p data-start=\"3150\" data-end=\"3335\">De specificiteit en het centrale activiteitsprofiel maken het bijzonder relevant voor <strong data-start=\"3229\" data-end=\"3334\">geavanceerd onderzoek naar het centraal zenuwstelsel, neuropeptidesignalering en de hypothalamus-hypofyse-as<\/strong>.<\/p>\n<p data-start=\"3337\" data-end=\"3483\"><strong data-start=\"3337\" data-end=\"3363\">Bestel PE-22-28 (10 mg)<\/strong> en het potentieel ervan te onderzoeken in geavanceerd neuropeptide-onderzoek, analyse van CNS-signalering en neuroendocrien onderzoek.<\/p>","protected":false},"excerpt":{"rendered":"<p>PE-22-28 \u2013 Proenkephalin-Derived Neuropeptide Research Compound Composition: PE-22-28 (10 mg lyophilized peptide powder)Category: PeptideForm: 10 mg vial with freeze-dried powderAdministration: Subcutaneous or central research application after reconstitution with sterile or bacteriostatic water (depending on study design) What is PE-22-28? PE-22-28 is a synthetic neuropeptide fragment derived from Proenkephalin A, an endogenous precursor protein involved in opioid and neuroregulatory signaling pathways. This peptide has been studied for its role in central nervous system modulation, particularly in relation to dopaminergic balance, prolactin regulation, and neuroendocrine signaling.Unlike classical opioid peptides, PE-22-28 demonstrates non-analgesic, regulatory activity, making it a distinct compound within neuropeptide research. In research settings, PE-22-28 (10 mg) is investigated for its influence on neurotransmitter regulation, motivational signaling, and hypothalamic-pituitary interactions. \u27a1\ufe0f Ideal for neuropeptide research, CNS signaling studies, and neuroendocrine pathway investigations. Key Research Findings Neuroregulatory Activity: Studied for its modulatory role within central neurotransmitter systems. Dopaminergic Interaction: Associated with regulation of dopamine-linked signaling pathways in experimental models. Prolactin Modulation Research: Investigated for its influence on prolactin-related neuroendocrine mechanisms. Non-Opioid Functional Profile: Does not exhibit classical opioid receptor agonism. CNS-Specific Interest: Primarily relevant to central rather than peripheral research models. Mechanism of Action PE-22-28 is believed to exert its effects through central neuroregulatory mechanisms, including: Neurotransmitter Modulation \u2192 Interaction with dopaminergic and neuroendocrine signaling circuits Hypothalamic Pathway Influence \u2192 Modulation of pituitary-related signaling cascades Receptor-Mediated Regulation \u2192 Indirect interaction with CNS receptor systems Central Activity Profile \u2192 Focused effects within the central nervous system Dosage &amp; Application Reconstitute with sterile or bacteriostatic water before use. Research concentrations vary depending on experimental design and protocol requirements.A 10 mg vial is suitable for multiple neuropeptide studies, dose-response experiments, or extended research protocols. Store the reconstituted solution refrigerated and use within 2\u20133 weeks. Storage Instructions Store at 2\u20138 \u00b0C (36\u201346 \u00b0F)Protect from light and moistureDo not freezeUse reconstituted solution within 2\u20133 weeks Why Choose PE-22-28 (10 mg)? PE-22-28 is valued in research environments for its unique position within proenkephalin-derived neuropeptides, offering insight into dopamine-regulated and prolactin-associated neuroendocrine pathways without direct opioid effects. Its specificity and central activity profile make it particularly relevant for advanced CNS research, neuropeptide signaling studies, and hypothalamic-pituitary axis investigations. Order PE-22-28 (10 mg) and explore its potential in advanced neuropeptide research, CNS signaling analysis, and neuroendocrine investigations.<\/p>","protected":false},"featured_media":126807,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_brand":[],"product_cat":[17,26,27],"product_tag":[],"class_list":["post-39654","product","type-product","status-publish","has-post-thumbnail","product_cat-all-products","product_cat-neuroandvascularprotection","product_cat-peptidesandresearchdrugs","entry","has-media","first","instock","shipping-taxable","purchasable","product-type-simple"],"acf":[],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 4.9.8 - aioseo.com -->\n\t<meta name=\"description\" content=\"PE-22-28 \u2013 Proenkephalin-Derived Neuropeptide Research Compound Composition: PE-22-28 (10 mg lyophilized peptide powder)Category: PeptideForm: 10 mg vial with freeze-dried powderAdministration: Subcutaneous or central research application after reconstitution with sterile or bacteriostatic water (depending on study design) What is PE-22-28? 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